Study Finds Smoking Linked to Breast Cancer Risk (HealthDay)

Wednesday, March 2, 2011 9:01 PM By dwi

TUESDAY, March 1 (HealthDay News) -- Both respiration and exposure to secondhand respiration appear to process the venture for boob cancer among postmenopausal women, newborn investigate shows.

Although early studies had institute lowercase or no unification between breast cancer and smoking, as more women smokers reach climacteric the connection haw be surfacing for the prototypal time, experts noted.

"The findings are essential because respiration was not previously thought to process the venture of boob cancer, but this think adds to the increasing grounds that it does," said lead scientist Dr. Karenic Margolis, a senior clinical investigator at HealthPartners Research Foundation in Minneapolis.

However, Susan Gapstur, vice chair of epidemiology for the dweller Cancer Society, said early investigate had shown some unification between smoking and boob cancer.

"When you place unitedly the embody of impact in the terminal some years, it calls for more studies," she said. "This think has answered that call."

"This certainly adds to the grounds that long-term respiration increases the venture for boob cancer," Gapstur said. "On the on the fling side, it appears that 20 eld after stopping the venture goes downbound to that of an average individual. I think that's beatific news."

Many venture factors for boob cancer cannot be changed, such as age, genetics and family story of the disease, Margolis noted.

"Now respiration crapper be additional to the list of things that crapper lower boob cancer venture that already include having children, breast-feeding, ownership alcohol activity low, avoiding coefficient gain, existence physically astir and avoiding hormone therapy with oestrogen plus progestin," she said.

The report is published in the March 1 online edition of the BMJ.

For the study, Margolis's assemble composed accumulation on 79,990 women aged 50 to 79 who took conception in the Women's Health Initiative study. Over 10 eld of follow-up, 3,250 women matured boob cancer.

As conception of the study, the women were asked if they smoked, had stopped smoking or had never smoked. The women were also asked about their exposure to old respiration at bag and at work.

The researchers institute that women who preserved had a 16 proportionality accumulated risk of nonindustrial boob cancer. Among women who quit, the accumulated venture was 9 percent, they added.

The large venture was for women who had preserved for 50 eld or longer, compared with women who never smoked, Margolis's aggroup found. The venture was also broad for women who started respiration when they were teenagers. Even after quitting, the venture continuing for up to 20 years, the researchers noted.

"We also observed some grounds that comprehensive exposure to supine smoking haw improve the venture of boob cancer," Margolis said.

Nonsmokers exposed to old respiration for more than 10 eld as children, more than 20 eld as adults at bag and more than 10 eld at work had a 32 proportionality accumulated venture of nonindustrial boob cancer, the researchers found.

However, the unification between boob cancer and old respiration was seen in those exposed to the large turn of supine respiration and "therefore more investigate is needed to confirm these findings," the researchers noted.

Dr. Paolo Boffetta, deputy administrator of the Tisch person Institute and Institute for Transitional Epidemiology at Mount desert School of Medicine in New York City and co-author of an accompanying journal editorial, said that "tobacco smoking, particularly when started early in life, haw increase the venture of boob cancer."

"This grounds is becoming stronger and stronger," he said. "In previous studies, the grounds was not so strong. It is only today that women who started respiration in large drawing are effort to the geezerhood where the venture of boob cancer is effort high."

Right now, the association between respiration and boob cancer is ease not a trusty thing, Boffetta said, "but, it is effort more likely."

More information

For more aggregation on boob cancer, meet the American person Society.


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