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MONDAY, Feb. 14 (HealthDay News) -- Obese men face a dramatically higher venture of ending from a hunch attack, regardless of whether or not they have another known venture factors for cardiovascular disease, a newborn conceive reveals.

The uncovering stems from an psychotherapy involving roughly 6,000 middle-aged men, and it suggests that there is something about carrying around immoderateness weight that contributes to hunch disease independent of venture factors much as broad blood pressure, diabetes, broad cholesterin and arterial disease.

What exactly that something is, however, relic unclear, though the researchers suggest that the habitual rousing that typically accompanies significant coefficient gain strength be the dynamical obligate behindhand the increased risk.

"Obese, middle-aged men have a 60 proportionality accumulated venture of ending from a hunch move than non-obese middle-aged men, modify after we cancel discover any of the effects of cholesterol, blood push and another cardiovascular risk factors," noted conceive author Jennifer Logue, a clinical lecturer of metabolic penalization with the British Heart Foundation's Cardiovascular Research Centre at the University of Glasgow, in Scotland. "This means [that] blubber itself haw be feat mortal hunch attacks through a bourgeois that we have not yet identified."

Logue and her colleagues inform their observations in the Feb. 15 online issue of Heart.

To explore the subject, the authors spent nearly 15 eld chase 6,082 male patients who were diagnosed with broad cholesterin but had no history of either hunch disease or diabetes.

Over the conceive period, the investigate team noted 214 hunch disease fatalities, along with another 1,027 hunch attacks and/or strokes that did not termination in death.

The team addicted the well-established theory that existence fat is linked to a greater quantity for having every of the artist venture factors linked to hunch disease.

That said, modify after judgement discover germane variables much as age and smoking history, the venture of modification among fat men -- those with a body mass index (BMI) between 30 and 39.9 -- was ease 75 proportionality higher than it was for non-obese men.

What's more, modify after also business for venture factors much as broad blood push and diabetes (as well as medication history), the quantity of experiencing a mortal hunch move was 60 proportionality greater among fat men, as compared with non-obese men.

The digit caveat: in and of itself, existence fat was not linked to a higher venture of experiencing a non-fatal hunch move or stroke.

Logue cautioned that boost investigate is necessary to confirm the findings, and to uncover the literal execution by which blubber itself is a risk bourgeois for mortal hunch attacks.

"Possible reasons allow portion chemicals that the fat cells are releasing. Or perhaps it is attendant to the fact that fat grouping tend to have large whist to cope with the additional stress of their large size, and this already stressed hunch does not manage to move to work during a hunch attack," she said.

"However, it certainly makes me conceive that we cannot meet impact cholesterol, blood push and diabetes in fat men without also considering their weight," Logue added. "We requirement to find easier and more effective ways to support grouping lose coefficient and find discover if losing coefficient can support turn the venture of mortal hunch attacks. We also requirement to devote far more resources to preventing blubber in the prototypal place."

Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles, said that the current conceive "provides boost evidence as to ground there needs to be orbicular efforts to prevent and impact obesity though style modification."

"While blubber is related with elevations in blood pressure, increased venture of diabetes and abnormal lipid levels, it has been less clear whether the accumulated venture of mortality related with blubber can be entirely explained by these well-established cardiovascular venture factors or whether another factors attendant to blubber haw also be contributing to immoderateness mortality risk," he noted.

Dr. philologue A. Mittleman, director of the Cardiovascular Epidemiology Research Unit with the Beth Israel Deaconess Medical Center, altruist Medical School in Boston, agreed.

"It's not astonishing that not every of the venture can be explained by traditional venture factors," he said. "But no digit conceive is feat to definitively answer the discourse as to what another mechanisms for venture might be. So the direct issue would ease move to be working towards overall coefficient reduction, to turn the venture for every of the pathways that we already know go along with obesity."

More information

For more on blubber and hunch disease, meet the American Heart Association .

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