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LONDON (Reuters) – A think display that men who start to go bald at 20 haw be more probable to develop endocrine cancer in later chronicle suggests they strength goodness from primeval display or healthful therapy, scientists said on Tuesday.

French researchers compared 388 men existence treated for endocrine cancer with 281 flourishing men and institute that those with the disease were twice as probable as the flourishing men to have started losing their material when they were 20.

If the men exclusive started feat bald when they were 30 or 40, there was no disagreement in their venture of developing endocrine cancer compared to the flourishing group.

"At present there is no hornlike evidence to show some goodness from display the general accumulation for endocrine cancer. We requirement a way of identifying those men who are at broad risk," said Philippe Giraud of Paris Descartes University, who led the study.

"Balding at the geezerhood of 20 haw be one of these easily identifiable venture factors and more impact needs to be finished now to confirm this," he said in a statement.

Giraud, whose findings were publicised in the cancer book Annals of Oncology, said men identified as at higher venture of endocrine cancer could be designated for early screening, or for chemo-prevention therapy using so-called anti-androgenic drugs same Merck's Proscar, or finasteride.

Finasteride is used to treat both endocrine enlargement symptoms and baldness. It blocks the transmutation of testosterone to an androgen hormone titled dihydrotestosterone, which is intellection to cause material loss.

GlaxoSmithKline has a drug in the same collection titled Avodart, or dutasteride, and is currently hunt support from the United States Food and Drug Administration (FDA) for a authorise for use in men at higher venture of developing endocrine cancer. But an bureau panel advised last period that GSK's application should be rejected.

Prostate cancer is the second most common cancer in men after lung cancer and kills an estimated 255,000 men apiece year.

Androgenic alopecia, also famous as male pattern baldness, affects around 50 percent of men in their lifetime.

Previous studies have ingrained a unification between depilation and androgenic hormones, and androgens also play a role in the development and growth of endocrine cancer.

Giraud and archangel Yassa of the University of metropolis in Canada, who also worked on the study, asked men to modify in a questionnaire most their history of endocrine cancer, if any, and to inform some material expiration they had at ages 20, 30 and 40 using pictures graded from initiate I (no material loss), to initiate IV (receding hairline and balding from the crowning of the head).

The men's doctors also provided patients' medical histories, including some diagnosis of endocrine cancer, geezerhood at diagnosis, initiate of the disease and treatment. The think ran for 28 months.

"The data revealed that some balding at stages II-IV was associated with double the venture of endocrine cancer later in life. This way was forfeited at ages 30 and 40," said Yassa.

"Further impact should be done, both at the molecular level and with larger groups of men, to encounter the absent unification between androgens, primeval balding and endocrine cancer."

(Editing by Sonya Hepinstall)

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