New Chemo Drug May Benefit Some Breast Cancer Patients (HealthDay)
Thursday, March 3, 2011 9:01 PM By dwi
WEDNESDAY, March 2 (HealthDay News) -- The newborn chemotherapy take eribulin extends the lives of metastatic boob cancer patients who hit received extensive treatment, according to a newborn study.
The researchers institute that among patients whose cancer had spread, those who took the take lived a norm of 2.5 months individual than those who received a physician-chosen communication -- 13.1 months versus 10.6 months.
The think included 508 women who were given eribulin and 254 women who received communication of the physician's choice, which was circumscribed as: some single-agent chemotherapy, hormonal or natural communication approved for cancer treatment; radiotherapy; or characteristic communication alone.
The most ordinary side personalty in both groups were fatigue and depletion of white murder cells. Numbness and discompose stemming from nerve damage were the most ordinary adverse event connected to eribulin that led women to drop out of the think (24, or 5 percent).
The study, famous as the EMBRACE trial, was funded by Eisai Inc., which markets eribulin. Dr. Javier Cortes, of the Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology in Barcelona, Spain, and colleagues published the findings in the March 3 online edition of The Lancet.
"This orbicular phase 3 think establishes a possibleness newborn accepted treatment for women with hard pretreated metastatic boob cancer, for whom there was previously no chemotherapy communication with proven survival benefit," the authors wrote.
In a attendant editorial, Drs. metropolis U. sculpturer and Harold J. Burstein, of the Dana-Farber Cancer Institute and altruist Medical School in Boston, said: "EMBRACE provides much needed, high-level grounds for chemotherapy use in patients with hard pretreated boob cancer. And that grounds suggests that the methods to impact modern boob cancer are growing, the treatment challenge in refractory disease is a little taste less daunting, and the communication results are a little taste better than they were before."
Commenting on the study, Dr. Stephanie Bernik, chief of preoperative oncology at Lenox Hill Hospital in New royalty City, said, "The findings of this effort are elating because they module displace eribulin into wider use. This take shows much promise, and it should certainly be included in additional trials to full establish its benefit."
"It would be interesting to see if the take offers the aforementioned goodness in women that hit not been treated with multiple drugs before exposure to eribulin," she added.
More information
The Metastatic Breast Cancer Network has more most metastatic boob cancer.
Source
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