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NEW YORK (Reuters Health) – People who ingest painkillers much as Motrin on a regular foundation haw be inferior probable to get sac cancer, according to a newborn review.

The researchers found a small quantity of the cancer in grouping taking medications called non-steroidal anti-inflammatory drugs, or NSAIDs, more than twice a week. That includes drugs much as naproxen, marketed as Aleve, and ibuprofen, or Advil.

They did not find a low venture of sac cancer in grouping who regularly took aspirin, also an anti-inflammatory.

"There's quite a aggregation of (research) showing that NSAIDs do protect against a variety of cancers," Dr. justice Djakiew, a cancer scientist at Georgetown University Medical Center in Washington, D.C., told Reuters Health.

The review, which was published in the American Journal of Epidemiology, adds hold to preceding studies that hit suggested that grouping who take NSAIDs haw hit a small venture of sac cancer as well as colon cancer and endocrine cancer.

It's possible, said Djakiew, who did not move in the current study, that "people that chronically spend Motrin and maybe another NSAIDs haw be effort an anti-cancer goodness that they're not alive of."

Bladder cancer is the sixth most common cancer in the U.S. According to the National person Institute, there were most 70,000 newborn cases diagnosed nationwide in 2010, and close to 15,000 deaths from the disease.

Researchers led by Dr. wife Daugherty from the National Institutes of Health compounded accumulation from threesome preceding studies. The authors of each of those studies had asked participants how frequently they took assorted kinds of medications, including Empirin and another NSAIDs, and then tracked how many of them were diagnosed with sac cancer over the mass years.

The studies included a amount of more than 500,000 grouping who were an cipher of 62 eld old at the beginning of the study. Researchers followed them for an cipher of 7 years.

During that time, most 2,500 grouping were diagnosed with sac cancer. solon than 4 out of 5 of them were men.

Of grouping who never took NSAIDs another than aspirin, most 0.54 percent - or 1 in 185 grouping - developed sac cancer. In comparison, 0.41 percent of grouping who took non-aspirin NSAIDs more than twice a hebdomad got sac cancer, or 1 in 244 people.

How often grouping took Empirin was not linked with how probable they were to get sac cancer.

Djakiew said there are lots of doable reasons why grouping who take NSAIDs regularly strength be inferior at venture for sac cancer. One of those doable explanations, he said, is that inflammation caused by bacterium or a virus, for example, makes the polymer mutations that lead to cancer more likely. By definition, NSAIDs revilement down on inflammation, and could thence turn the quantity of a cancer developing and spreading.

In an email to Reuters Health, Daugherty said that NSAIDs haw prevent the growth of sac cancer cells - and that anti-inflammatories another than Empirin strength be better at it than aspirin.

But the think cannot establish that NSAIDs are answerable for lowering the venture of sac cancer, and the findings don't mean that taking NSAIDs every period is the prizewinning pick for everyone. Such drugs hit lateral effects, including ulcers.

"Based on our results, it would be early to make recommendations to patients" to take NSAIDs, Daugherty said.

SOURCE: http://bit.ly/iklzBs American Journal of Epidemiology, online March 2, 2011.

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