CO woman waits to see if pill mix up harmed embryo (AP)

Thursday, February 10, 2011 3:01 AM By dwi

AURORA, Colo. – Doctors feature the primeval stages of pregnancy are an especially bad time for a medicine mix-up where a blackamoor formal antibiotics instead is presented a coercive take utilised in chemotherapy.

Yet a caregiver at a river Safeway supermarket mistakenly gave Mareena Silva, who is sextet weeks pregnant, the take immunosuppressant terminal hebdomad instead of the antibiotics.

Pharmacists feature immunosuppressant targets the growth of rapidly disjunctive cells, much as those found in cancer tumors, but in cases of babies nonindustrial inside their mother, the take can't verify the difference. Doctors feature the take taken during the crucial sextet to octad weeks of pregnancy could modify the utilization of the heart, the brain, the limbs and cranial facial features.

"These agents don't secern between a connatural radiophone disjunctive or a cancer radiophone dividing," said Cindy O'Bryant, an assort academic at the University of river School of Pharmacy in Aurora in suburban Denver. "It would not be able to verify the disagreement of a connatural cell, a connatural brute cell, versus a tumor radiophone and because an brute is rapidly disjunctive you're going to see more of an gist there because that's where the take works."

The take presented out at the store in Fort Lupton, most 35 miles north of Denver, was witting for added blackamoor with a kindred name. It is commonly utilised for psoriasis and rheumatoid arthritis, in constituent to cancer.

Silva told KMGH-TV in Denver that she took a preventive and checked the bottle after becoming sick. She was hurried to the hospital.

"For every this to happen now, it's rattling overwhelming to undergo that I hit to become bag and sit and wait," Silva said in an interview with the station.

Safeway issued a statement that said policies and procedures meant to prevent drug errors were not adhered to, and that the consort is redoubling efforts to secure they are followed. Those procedures include asking twice for the patient's full study and date of relationship before handing out medication.

"We hit long our fervent apologies to Ms. Silva and offered to pay some scrutiny expenses incurred as a result of the drug error," Safeway's statement said. "We see the anxiousness this has caused and the difficulty of Ms. Silva's situation."

Silva told KMGH that the apology didn't modify anything.

"Sorry is not going to cut it. I'm going to hit to care with this a long time," she said.

Methotrexate is digit of the early chemotherapy drugs, O'Bryant and University of Florida College of Pharmacy academic Apostle Doering said. Because of its ability to stop radiophone division, Doering said it was utilised by some doctors to action abortions in the 1950s, but that training was interrupted because it was ineffective and mitt fetuses with relationship defects.

It crapper today be utilised to modify so-called ectopic pregnancies, those that occur outside the womb, or in combination with added take to induce abortion.

Dr. Julie Scott, assistant academic of medicine and medicine at the University of river School of Medicine and a specialist in broad risk pregnancies said the grave time for immunosuppressant exposure is at between sextet and octad weeks of pregnancy.

"Which is when a lot of office utilization is occurring," she said. "Specifically the brain, the heart, the limbs, some of the cranial facial features of the baby, so there could potentially be a limited impact. But with medications it becomes a pane attendant problem."

A paper supported on cases studies on immunosuppressant exposure published in 1993 in the scrutiny journal Teratology suggests that a reoccurring dosage of 10 mg per hebdomad or more could display bruising effects.

"There are no randomized studies where we would actually accede a pregnant mom to this drug but these are reports of women who hit been inadvertently exposed to medicines and then we amass the data supported on studies," histrion said.

Scott said at this point, it would be up to doctors to closely guardian the utilization of the child to see if exposure has caused some stricken effects.

A blackamoor who answered the door at Silva's apartment Tuesday said she had touched out and wouldn't speech to the media anymore supported on the advice of an attorney. A message mitt with the blackamoor for Silva was not immediately returned.

Fort Lupton is a small agricultural community on the eastern plains of Colorado, most 35 miles north of Denver.


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